Symposium
on Ion channels: from atomic resolution physiology to functional genomics, held
at the Novartis Foundation, London, 12–14 June 2001
Editors:
Gregory Bock (Organizer) and Jamie A. Goode
This
symposium is based on a proposal made by Mark Sansom
Mark
S. P. Sansom
Introduction:
stretching the envelope in structure–function studies of ion channels
Nigel
Unwin
Structure
of the acetylcholine-gated channel
Katjuša
Brejc, Willem J. van Dijk, August B. Smit and
Titia K. Sixma
The 2.7 Å structure of AChBP, homologue of the ligand-binding domain of the
nicotinic acetylcholine receptor
Abstract
Discussion
Alok
K. Mitra, Gang Ren, Vijay S. Reddy, Anchi Cheng
and Alexandrine Froger
The architecture of a water-selective pore in the lipid bilayer visualized
by electron crystallography in vitreous ice
Abstract
Discussion
Dax
Fu, Andrew Libson
and Robert Stroud
The structure of GlpF, a glycerol conducting channel
Abstract
Discussion
Mark
S. P. Sansom, Peter Bond, Oliver Beckstein, Philip C. Biggin, José Faraldo-Gómez,
Richard J. Law, George Patargias
and D. Peter Tieleman
Water in ion channels and pores—simulation studies
Abstract
Discussion
Benoit
Roux
What
can be deduced about the structure of Shaker from available data?
Abstract
Discussion
Stefano
Garofoli, Gennady Miloshevsky, Vladimir L. Dorman and
Peter C. Jordan
Permeation energetics in a model potassium channel
Abstract
Discussion
Jacqueline
M. Gulbis
The β subunit of Kv1 channels: voltage-gated enzyme or safety
switch?
Abstract
Discussion
E.
Perozo, L. G. Cuello, D. M. Cortes, Y.- S. Liu
and P. Sompornpisut
EPR approaches to ion channel structure and function
Discussion
General discussion I: From
structure to channel physiology
Senyon
Choe, Susan Cushman, Kent A. Baker
and Paul Pfaffinger
Excitability is mediated by the T1 domain of the voltage-gated potassium
channel
Abstract
Discussion
Michelle
M. Pirruccello, Nikolaus Grigorieff and
Joseph A. Mindell
Electron diffraction of a bacterial ClC-type chloride channel
Abstract
Discussion
John
B. C. Findlay
and Michael A. Harrison
A protein chemical approach to channel structure and function: the proton
channel of the vacuolar H+-ATPase
Abstract
Discussion
Anthony
Auerbach
Acetylcholine receptors, between closed and open
Abstract
Discussion
David
B. Sattelle, Emmanuel Culetto, Marta Grauso, Valérie Raymond, Christopher
Franks and
Paula Towers
Functional genomics of ionotropic acetylcholine receptors in Caenorhabditis
elegans and Drosophila melanogaster
Abstract
Discussion
Final
general discussion
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