Contents

Symposium on Inflammatory bowel disease—crossroads of microbes, epithelium and immune systems, held at the Novartis Foundation, London, 25–27 November 2003

Editors: Derek Chadwick (Organizer) and Jamie Goode

This symposium is based on a proposal made by Derek Jewell and Bill Roediger

Derek Jewell 
Chair’s introduction

John D. Rioux 
Progress towards identifying inflammatory bowel disease susceptibility genes
Abstract
Discussion

T. Ahmad 
Phenotype-determining genes in inflammatory bowel disease
Abstract
Discussion

Dermot Kelleher, Richard Farrell and Ross McManus 
Pharmacogenetics of inflammatory bowel disease
Abstract
Discussion

G. T. Macfarlane, E. Furrie and S. Macfarlane 
Bacterial milieu and mucosal bacteria in ulcerative colitis
Abstract
Discussion

Y. R. Mahida and R. N. Cunliffe 
Defensins and mucosal protection
Abstract
Discussion

W. E. W. Roediger 
Intestinal mycoplasma in Crohn’s disease
Abstract
Discussion

John H. Cummings and San Choon Kong 
Probiotics, prebiotics and antibiotics in inflammatory bowel disease
Abstract
Discussion

Andrei I. Ivanov, Asma Nusrat and Charles A. Parkos 
The epithelium in inflammatory bowel disease: potential role of endocytosis of junctional proteins in barrier disruption
Abstract
Discussion

Peter R. Gibson 
Apoptosis or necrosis—colonic epithelial cell survival
Abstract
Discussion

Ken Takeuchi, Laurence Maiden and Ingvar Bjarnason 
Genetic aspects of intestinal permeability in inflammatory bowel disease.
Abstract
Discussion

Fiona Powrie and Holm Uhlig 
Animal models of intestinal inflammation: clues to the pathogenesis of inflammatory bowel disease
Abstract
Discussion

Holm H. Uhlig, Christian Mottet and Fiona Powrie 
Homing of intestinal immune cells
Abstract
Discussion

S. Ghosh 
Anti-TNF therapy in Crohn’s disease
Abstract
Discussion

Final discussion

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