The genetics of autoimmunity
Open meeting presented in collaboration
with the Royal Society of Medicine and the Physiological Society
To be held at The Geological Society, Burlington House, Piccadilly, London W1
Closing date for registrations:
Friday 18th June 2004
Register Now!
It is now well
recognized that immunological diseases (autoimmune and allergic disorders) result from the combined effects of environmental triggers and inherited
susceptibility genes. Immunologic investigations of human autoimmune diseases have indicated that patients with organ specific autoimmunity have activated, autoreactive T cells specific for the target tissue. However, conventional immunologic studies have not been fruitful for elucidating the next level of pathogenesis of spontaneous autoimmune diseases, especially in humans. Therefore, there has been great interest in
identifying the genes that confer susceptibility to autoimmune diseases, with the hope that
this will provide valuable clues about pathogenesis and therapeutic possibilities. The objective of this meeting is to discuss the genes that may be associated with autoimmunity, how they can be identified, and how the functions of the gene products can be elucidated.
Presentations will include genome-wide approaches to dissecting tolerance and autoimmunity, genetic variants influencing autoimmune disease, functional genetic approaches in Coeliac Disease, and gene mapping in asthma and psoriasis.
| 1000 |
Welcome
Gregory BOCK
The Novartis Foundation,
London, UK |
| 1005 |
Chair's
introduction
Abul ABBAS
University of California San Francisco, USA |
| 1010 |
Mapping genes for asthma and psoriasis
Juha KERE
Karolinska Institute, Huddinge, Sweden |
| 1050 |
Genes involved in immune tolerance and autoimmunity
Abul ABBAS
|
| 1130 |
Coffee |
| 1150 |
Genetics of lupus in mice
Edward WAKELAND
The University of Texas Southwestern Medical
Center at Dallas, USA |
| 1230 |
Human SLE
Tim VYSE
Rheumatology Section, Imperial College, London, UK |
| 1310 |
Lunch |
| 1400 |
A functional genetics approach to unravel molecularpathways in Coeliac Disease
Cisca WIJMENGA
University Medical Center, Utrecht, The Netherlands |
| 1440 |
Genome-wide approaches to dissecting toleranceand autoimmunity
Chris GOODNOW
John Curtin School of Medical Research, Canberra, Australia |
| 1520 |
Tea |
| 1540 |
Genetic variants influencing autoimmune disease
Linda WICKER
Cambridge Institute for Medical Research,
Addenbrookes Hospital, Cambridge, UK |
| 1620 |
Population and medical genetics: what have we learned?
David GOLDSTEIN
Department of Biology, UCL, London, UK |
| 1700 |
Chair's
closing remarks
Abul ABBAS |
Please note that this programme may be
subject to change.
All are welcome, but pre-registration is essential. A registration fee of
£75 (£55 RSM/PhySoc members, £25 for students) will be charged, covering documentation, lunch and
tea/coffee.
Cancellations
Should be confirmed in writing and accompanied by your receipt. An administrative charge of £15 will be made on all cancellations received before
Friday 18th June 2004. After this date we regret fees will not be refunded. Substitutions may be made at any time without charge.
To register, use the online
form, or please contact:
Sharan Gallagher
Academic Conference Department
Royal Society of Medicine
1 Wimpole Street
London W1G 0AE
fax: 020 7290 2977
tel: 020 7290 3946
e-mail: events@rsm.ac.uk
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